Titanium (Ti) cages may be superior to polyetheretherketone (PEEK) cages in lumbar interbody fusion: a systematic review and meta-analysis of clinical and radiological outcomes of spinal interbody fusions using Ti versus PEEK cages

Interbody cages are commonly used to augment interbody fusion. Commonly materials include titanium (Ti) and polyetheretherketone (PEEK), with their inherent differences. The aim of this study is perform a systematic review meta-analysis compare between the various clinical radiological outcomes Ti PEEK spinal cages. A comparing in patients undergoing fusion was performed. PubMed, Scopus, Web Science, Embase, Cochrane Central Register Controlled Trials database were searched. All studies that compared who underwent included. Subgroup analyses performed differentiate had cervical lumbar total 11 articles identified, 743 patients. Spinal rates at final follow-up did not differ (OR 1.50, 95% CI 0.57–3.94, P = 0.41), although fusion, demonstrated superior 2.12, 1.05–4.28, 0.04). In non-infective etiologies, higher rate cage subsidence (RR 2.17, 1.13–4.16, 0.02). Both types similar operating time, postoperative hematoma formation, neuropathic pain, segmental angle correction outcome improvement. spine conditions, may be option due rate. III.